Sunday, 23 July 2017

Individualised And Effective Treatment For Segmental Vitiligo

Segmental Vitiligo is characterized by the appearance of patches on one side or segment of the body. The absence of skin pigment cell, melanocyte results in this condition.

The major features of segmental vitiligo are, begins at a younger age, it grows fastly, hairs over the patch and adjacent also become white and medical treatments are not effective Resorting to ineffective conventional treatment for a prolonged time will result in a condition called (treatment)modified vitiligo. Repeated treatment like psoralens (Bakuchi) irritates the skin, and results in color and skin texture mismatch, like irregular pigmentation, scarring, and mixture of dark and light colors. Such modifications might create a problem in getting a satisfactory result even after effective treatment option like noncultured epidermal suspension transplantation.

Individualised approach at MelanoSite

What differentiates MelanoSite and Dr. Anantha Prasad Holla from other treatment providers is the exclusive experience, unmatched expertise, dedicated approach and care they show towards each and every patient, as well as each and every vitiligo type. Prior commencing treatment Dr. Holla will take detailed consultation and evaluation of vitiligo. The type of vitiligo, site of vitiligo, stage of vitiligo, size of the patches, the age of the patient, age at onset of vitiligo, previous treatments and their effect on vitiligo, underlying medical conditions. Compared to conventional treatment which treats all the patients in the same method, it is a new, innovative method which helps the patient achieve satisfactory results. This individualized approach is effective in the patients who had failures in previous treatments. Individualised treatment focuses on “What your vitiligo needs”. It’s not customized treatment where it is “What you want”. Treatment decision is purely in result oriented and cost-effective manner.

Having a decade of exclusive experience in vitiligo treatment and research, Dr. Holla has successfully treated 4500 vitiligo patches and near to 1000 segmental vitiligo patches using his advanced cell transplantation method, noncultured epidermal suspension transplantation. He is specialized in the surgical vitiligo treatment of difficult to treat vitiligo like patches on, Acral area (fingers, hands, toes, feet), eyelids, lip, joints, genital area, areola and nipple, ear and large areas. His expertise services are available in Bangalore and New Delhi with a prior booking of appointments on particularly fixed schedules.

The treatment procedure 

The severity of cell damage in segmental vitiligo such that the melanocytes or the stem cells responsible for regeneration of melanocytes are damaged beyond repair not only over skin but also over hair roots. So, both skin and hairs over it become white. In most of the cases, conventional medical treatment is ineffective. Advanced cell transplantation method proved to be the best option for treating this. This is done when the white spot is not growing (stable) in last six months to one year. A very thin transparent skin layer will be taken from the normal area and skin cell suspension is prepared using a unique method innovated by Dr. Holla. Taking uniform ultra-thin skin layer and preparation of cell suspension with high viable cell yield needs immense expertise. Later cell suspension transplanted over the recipient area using the special technique. The preparation of recipient site and placement of cell suspension and putting dressing in right manner needs utmost experience. Every step in the cell transplantation is very important to achieve satisfying results. If done by an expert, in right manner and in right time this procedure helps attain almost near normal color with texture match and even pigmentation of white areas over white patches over the time.

Why to go for Vitiligo Surgery?

The main reason why people choose vitiligo surgery is when the medical treatments fail to achieve pigmentation.

The basic principle of surgical treatment in vitiligo is to achieve repigmentation of the de-pigmented area. However, vitiligo surgery doesn’t target the underlying destructive process. Sometimes it is combined with various medical modalities to achieve a better outcome.

Depending on the type of vitiligo, site of vitiligo and extent of vitiligo different surgical modalities are available. However, non-cultured epidermal suspension transplantation is the most advanced as well as effective option in every eligible vitiligo patch.

For the best result, an appropriate patient selection is needed. Not all patients are suitable for vitiligo surgery. Following are the main factors considered.
  • The age of the patient
  • Patient expectations
  • Disease stability
  • Size and location of the vitiligo patch
  • Method of vitiligo surgery

 What is Non-cultured epidermal suspension transplantation?

In this procedure, an ultra-thin skin graft is processed in a special chemical which separates cells. The process is also known as Melanocyte transplantation(a misnomer) or Melanocyte-Keratinocyte transplantation. In non-cultured epidermal suspension transplantation, various modifications are available. Cold trypsinization method achieves a better outcome due to the high viable yield of cells. There are many clinics, which claim to do this procedure but only very few centers give a consistently high percentage of good results. A dedicated, exclusively experienced center with advanced treatment option which is effective in every vitiligo patch is a key to high success rates.

Dr. Anantha Prasad Holla is a trained dermatologist with exclusive experience in advanced vitiligo surgical options. He has an exclusive vitiligo treatment and research experience for almost 8 yrs and did more than 1750 successful cell transplantation procedures so far. He has extraordinary experience in treating “difficult to treat” vitiligo and treating large areas in one sitting. He is the medical director of the best vitiligo clinic in India, which offers result oriented Vitiligo Surgery with advanced cell transplantation options. The center also offers advanced medical management options for those patients who are not eligible for surgical management.

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Treatment for Vitiligo

As a dermatologist, I had a lot of experience with patients with vitiligo. Vitiligo disease is defined as a skin condition in which milky white patches appears on the different part of the body due to cell depigmentation. Pigments are the special skin of cells responsible for the coloration of the body.

Types Of Vitiligo

Classification of vitiligo is categorized into two types. They are:

1) Segmental vitiligo
Vitiligo patches limited to a segment of the body, usually in a non-segmental pattern. This form of vitiligo has a younger onset.

2) Non-segmental vitiligo
In this type of vitiligo patches appears in a very symmetrical way. Its size increases gradually. The third class of vitiligo is a combination of above both. Vitiligo is classified into other groups which are subgroups of segmental an non-segmental vitiligo as on it appears on several parts of the body but small in size.

Treatment for Vitiligo

It is done in order to vitiligo treatment. The choice of therapy depends upon the number of patches, the size of patch & on patient’s preference for the treatment.Cures for vitiligo include Surgical Therapy, topical corticosteroids, topical immunomodulators, phototherapy etc.

Sunscreens protect the normal skin from burning caused by the sun. It should protect the depigmented cell from the burn and reduce the tanning caused to the normal skin.

Use of cosmetics to make the patches less visible to others is another choice used by individuals. Self-tanning lotions and camouflages are available nowadays during the course of treatment of leucoderma.
There are different types of surgical treatments.
  • Tissue Grafting:- Like Punch grafting, Split skin grafting and Suction blister grafting
  • Camouflage Tattooing:- Permanent camouflage using artificial pigments into the lesions.
  • Cellular Transplantation:- NCES/Melanocyte Transplantation, Cultured Melanocyte Transplantation

Surgical Treatment

If the de-pigmented patch does not increase in size for a period of two years, it is said to be stable. It is the right time to perform vitiligo surgery. Surgical treatment consider for the patients having the following facts,
  • Vitiligo has not changed over a period of one year.
  • A failed medical line of treatment.
  • No New hypopigmented patches should develop
  • All wound should heal with normal pigmentation.

Cost of Vitiligo Treatment

Cost of skin disorder treatment is considerably cheap in India when compared with other countries with the same quality. So more and more foreigners attracting towards India for skin vitiligo treatments.

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Individualised And Effective Treatment For Segmental Vitiligo

Segmental Vitiligo is characterized by the appearance of patches on one side or segment of the body. The absence of skin pigment cell, me...