Sunday, 23 July 2017

Individualised And Effective Treatment For Segmental Vitiligo

Segmental Vitiligo is characterized as appearance of patches on one side or segment of the body. The absence of skin pigment cell, melanocyte results in this condition.

The major features of segmental vitiligo are , begins at a younger age, it grows fastly, hairs over the patch and adjacent also become white and medical treatments are not effective Resorting to inefective conventional treatment for a prolonged time will result in a condition called (treatment)modified vitiligo. Repeated treatment like psoralens (Bakuchi) irritates the skin, and results in colour and skin texture mismatch, like irregular pigmentation, scarring and mixture of dark and light colours. Such modifications might create problem in getting satisfactory result even after effective treatment option like non cultured epidermal suspension transplantation.

Individualised approach at MelanoSite

What differentiates MelanoSite and Dr. Anantha Prasad Holla from other treatment providers is the, exclusive experience, unmatched expertise, dedicated approach and care they show towards each and every patient, as well as each and every vitiligo type. Prior commencing treatment Dr. Holla will take detailed consultation and evaluation of vitiligo. The type of vitiligo, site of vitiligo, stage of vitiligo, size of the patches, age of the patient, age at onset of vitiligo, previous treatments and their effect on vitiligo, underlying medical conditions. Compared to conventional treatment which treats all the patients in the same method, it is a new, innovative method which helps the patient achieve satisfactory results. This individualised approach is effective in the patients who had failures in previous treatments. Individualised treatment focuses on “What your vitiligo needs”. It’s not customized treatment where it is about “What you want”. Treatment decision is purely on result oriented and cost effective manner.

Having a decade of exclusive experience in vitiligo treatment and research, Dr. Holla  has  successfully treated 4500 vitiligo patches and near to 1000 segmental vitiligo patches using his advanced cell transplantation method, non cultured epidermal suspension transplantion. He is specialized in the surgical vitiligo treatment of difficult to treat vitiligo like patches on , Acral area (fingers, hands, toes, feet), eyelids, lip, joints, genital area, areola and nipple, ear and large areas. His expertised services are available in Bangalore and New Delhi with prior booking of appointments on particular fixed schedules.
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The treatment procedure 

The severity of cell damage in segmental vitiligo such that the melanocytes or the stem cells responsible for regeneration of melanocytes are damaged beyond repair not only over skin but also over hair roots. So, both skin and hairs over it become white. In most of the cases, conventional medical treatment is ineffective. Advanced cell transplantation method proved to be the  best option for treating this. This is done when the white spot is not growing (stable) in last six months to one year. A very thin transparent skin layer will be taken from the normal area and skin cell suspension is prepared using an unique method innovated by Dr. Holla. Taking uniform ultra-thin skin layer and preparation oc cell suspension with high viable cell yield needs immense expertise. Later cell suspension transplanted over the recipient area using special technique. The preparation of recipient site and placement of cell suspension and putting dressing in right manner needs utmost experience. Every step in the cell transplantation is very important to achieve satisfied results. If done by expert, in right manner and in right time this procedure helps  attain almost near normal colour with texture match and even pigmentation of white areas over white patches over the time.

Why to go for Vitiligo Surgery?

The main reason why people choose vitiligo surgery is when the medical treatments fail to achieve pigmentation.

The basic principle of surgical treatment in vitiligo is to achieve repigmentation of the de-pigmented area. However, vitiligo surgery doesn’t target the underlying destructive process. Sometimes it is combined with various medical modalities to achieve a better outcome.

Depending on the type of vitiligo, site of vitiligo and extent of vitiligo different surgical modalities are available. However, non cultured epidermal suspension transplantation is the most advanced as well as effective option in every eligible vitiligo patch.

For the best result, an appropriate patient selection is needed. Not all patients are suitable for vitiligo surgery. Following are the main factors considered.
  • The age of the patient
  • Patient expectations
  • Disease stability
  • Size and location of the vitiligo patch
  • Method of vitiligo surgery

 What is Non cultured epidermal suspension transplantation?

In this procedure, a ultra-thin skin graft is processed in a special chemical which separates cells. The process is also known as Melanocyte transplantation(a misnomer) or Melanocyte-Keratinocyte transplantation. In non cultured epidermal suspension transplantation, various modifications are available. Cold trypsinization method achieves a better outcome due to high viable yield of cells. There are many clinics, which claim to do this procedure but only very few centres give a consistent high percentage of good results. A dedicated, exclusively experienced centre with advanced treatment option which is effective in every vitiligo patch is a key for high success rates.

Dr. Anantha Prasad Holla is a trained dermatologist with exclusive experience in advanced vitiligo surgical options. He has an exclusive vitiligo treatment and research experience of almost 8 yrs and did more than 1750 successful cell transplantation procedures so far. He has extraordinary experience in treating “difficult to treat” vitiligo and treating large areas in one sitting. He is medical director of the best vitiligo clinic in India, which offers result oriented Vitiligo Surgery with advanced cell transplantation options. The centre also offers advanced medical management options for those patients who are not eligible for surgical management.

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Treatment for Vitiligo

As a dermatologist I had lot of experience with patients with vitiligo. Vitiligo disease is defined as a skin condition in which milky white patches appears on different part of body due to cell depigmentation. Pigments are special skin of cells responsible for coloration of body.

Types Of Vitiligo

Classification of vitiligo is categorized into two types. They are:

1) Segmental vitiligo
Vitiligo patches limited to a segment of the body, usually in a non segmental pattern. This form of vitiligo has a younger onset.

2) Non segmental vitiligo
In this type of vitiligo patches appears in a very symmetrical way. Its size increase gradually. Third class of vitiligo is combination of above both. Vitiligo is classified in other groups which is sub groups of segmental an non segmental vitiligo as on it appears on several part of body but small in size.

Treatment for Vitiligo

It is done in order to vitiligo treatment. The choice of therapy depends upon the number of patches, the size of patch & on patient’s preference for the treatment.Cures for vitiligo includes Surgical Therapy, topical corticosteroids, topical immunomodulators, phototherapy etc.

Sunscreens protect the normal skin from burning caused by the sun. It should protect the depigmented cell from burn and reduce the tanning caused to the normal skin.

Use of cosmetics to make the patches less visible to others is another choice used by individuals. Self tanning lotions and camouflages are available now-a-days during the course of treatment of leucoderma.
There are different types of surgical treatments.
  • Tissue Grafting:- Like Punch grafting, Split skin grafting and Suction blister grafting
  • Camouflage Tattooing:- Permanent camouflage using artificial pigments into the lesions.
  • Cellular Transplantation:- NCES/Melanocyte Transplantation, Cultured Melanocyte Transplantation

Surgical Treatment

If the de-pigmented patch does not increase in size for a period of two years, it is said to be stable. It is the right time to perform vitiligo surgery. Surgical treatment consider for the patients having the following facts,
  • Vitiligo has not changed over a period of one year.
  • Failed medical line of treatment.
  • No New hypopigmented patches should develop
  • All wound should heal with normal pigmentation.

Cost of Vitiligo Treatment

Cost of skin disorder treatment is considerably cheap in India when compared with other countries with same quality. So more and more foreigners attracting towards India for skin vitiligo treatments.

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Individualised And Effective Treatment For Segmental Vitiligo

Segmental Vitiligo is characterized as appearance of patches on one side or segment of the body. The absence of skin pigment cell, melano...